Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Published:May 15, 2020 DOI:https://doi.org/10.1016/j.cell.2020.04.026 SARS-CoV-2 infection induces low IFN-I and -III levels with a moderate ISG response Strong chemokine expression is consistent across in vitro, ex vivo, and in vivo models Low innate antiviral defenses and high pro-inflammatory cues contribute to COVID-19

The link address is: https://www.cell.com/cell/fulltext/S0092-8674%2820%2930489-X#%20